Microsoft open-sources PIKE-RAG: a new benchmark for professional RAG systems, increasing multi-step reasoning accuracy by 30%!

Written by
Iris Vance
Updated on:July-01st-2025
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Microsoft PIKE-RAG system, a new breakthrough in professional field question answering, with an accuracy rate soaring by 30%!

Core content:
1. Technological innovation: deep extraction of domain knowledge and construction of logical reasoning chain
2. Performance crushes traditional solutions: test set accuracy rate greatly improved
3. Extremely fast deployment and enterprise-level landing scenarios: medical, pharmaceutical, industrial manufacturing, etc.

Yang Fangxian
Founder of 53AI/Most Valuable Expert of Tencent Cloud (TVP)

 

Introduction:

Traditional RAG systems are unable to handle professional domain knowledge? Microsoft's latest open source(Professional Knowledge and Logic Enhanced Generation System) completely breaks this deadlock! Through the innovative knowledge extraction-logical reasoning dual engine design, the accuracy rate is increased to 87.6% in complex question-answering tasks in the fields of medicine, pharmaceuticals, industrial manufacturing, etc. This article will deeply analyze its three major technological breakthroughs and provide practical medical scenario code!



text:

1. Technological innovation

  • •  Deep extraction of domain knowledge :
    • • Context-aware segmentation technology (improves semantic coherence by 50%)
    • • Automatic alignment of professional terms (solves the problem of searching industry jargon)
    • • Multi-granularity knowledge extraction (supporting molecular-level industrial formula analysis)
  • •  Logical reasoning chain construction :
    # Example of multi-step reasoning in medical scenarios  
    pipeline = PIKE_RAG(  
        task= "Develop a cancer treatment plan" ,  
        steps=[  
            "Retrieve patient medical history → analyze test reports → match clinical guidelines → generate personalized solutions"  
        ]  
    )  
  • •  Dynamic task decomposition :
    • • Automatically identify question type (fact retrieval/innovation generation)
    • • Intelligently call different processing pipelines (as shown in the figure)

2. Performance crushes traditional solutions

Test Set
Traditional RAG
Improvement
HotpotQA
87.6%
62.1%
+25.5%
2WikiMultiHopQA
82.0%
58.3%
+23.7%
Pharmaceutical QA (Internal)
91.2%
67.8%
+23.4%



3. Rapid deployment within 5 minutes

  1. 1.  Environmental preparation :
    git  clone  https://github.com/microsoft/PIKE-RAG  
    cp  .env.example . env # Fill in the API key    
  2. 2.  Construction of medical knowledge base :
    # config/medical.yaml  
    knowledge_extraction:  
      method: "biobert" # Biomedical-specific embedding     
      chunk_size: "dynamic" # Dynamic paragraph segmentation     
  3. 3.  Start the inference service :
    python examples/medical_qa.py --question "Second-line treatment options for EGFR-mutated lung cancer"

4. Enterprise-level landing scenarios

  • •  Pharmaceutical R&D :
    • • Automatically analyze molecular formula associations in patent documents
    • • Multi-dimensional verification of clinical trial plans
  • •  Industrial Manufacturing :
    • • Causal chain reasoning of equipment failure manual (accuracy 92.4%)
    • • Cross-language technical documentation alignment
  • •  Financial compliance :
    • • Multi-level correlation analysis of regulatory provisions
    • • Automatically generate audit reports

5. Advanced Tuning Techniques

  • •  Hybrid search strategy :
    retriever = HybridRetriever(  
        dense=ColBERT(medical_embedding),  
        sparse=Elasticsearch(keyword_boost= 2.0 )  
    )  
  • •  Logic verification module :
    reasoning:  
    validators:
        - type: "fact_check"
          sources:  [ PubMedClinicalTrials.gov ]  
        - type: "logic_consistency"
          rules: "Medical Decision Tree v3.2"  

Developer Benefit Package

????  Free resources :

  • • Pre-built pharmaceutical knowledge graph (https://aka.ms/pike-rag-medkg)
  • • Industrial Troubleshooting Sample Library (https://aka.ms/pike-rag-industry)
  • • Join the PIKE-RAG technical community (https://aka.ms/pike-rag-slack) to get exclusive support
  • • Quote:
@misc{pike-rag,  
  title={PIKE-RAG: Domain-Specific Knowledge Augmented Generation with Rationale Chains},  
  author={Microsoft Research AI},  
  year={2025}  
}  

Summarize:

The launch of PIKE-RAG marks the entry of RAG systems in professional fields into the "precise reasoning era". Its innovative knowledge-logic dual-drive architecture achieves accuracy close to expert level while maintaining generation flexibility. Come to GitHub to explore this rising star of professional AI now!